Police are currently in attendance at the Royal Infirmary following reports of a suspicious male in the grounds.
One hospital source has claimed the man is armed with a knife and officers are at the scene trying to locate him.
A Police Scotland spokeswoman said: “Police in Edinburgh are in attendance following a report of a possible suspicious male in the grounds of the Edinburgh Royal Infirmary.
“Inquiries are ongoing. This is not being treated as a firearms incident.”